Sindrome hipereosinofílico como manifestación de larva migrans visceral por Toxocara canis

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Titre du document / Document title

Sindrome hipereosinofílico como manifestación de larva migrans visceral por Toxocara canis = Hypereosinophilic syndrome as manifestation of Larva migrans visceral by Toxocara canis

Auteur(s) / Author(s)

CORONEL-MARTINEZ Diana Leticia⁽¹⁾ ; MALDONADO-VELASQUEZ Rocio⁽¹⁾ ; CARRENO-MANJARREZ Roberto⁽¹⁾ ; GAMBOA-MARRUFO José D.⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾Departamento de Medicina Interna y Reumatología Pediátrica, Hospital Infantil de México Federico Gómez, México, D.F., MEXIQUE

Résumé / Abstract

Introduction. The hypereosinophilic syndrome is defined by excessive high levels of eosinophils in peripheral blood, that can lead to organic damage. The diseases associated to this syndrome mostly include: allergic diseases, parasitic diseases (being toxocariasis one of the most important), connective tissue diseases, malignancies and immunodeficiencies. In the present paper we report a patient in which the main clinical signs for clinical approach were: fever, pallor, eating of earth and hypereosinophilic syndrome. Case report. The patient, a 2 years old female infant, used to have contact with dogs, birds and chickens. Her history of present illness was characterized by fever until 40 centigrades above 4 months, pallor above a month, and eating of earth above 6 months. In the physical examination the main findings were generalized pallor, unique anterior left cervical adenopathy, liver at 5 cm from the right rib edge, and spleen at 3 cm form left rib edge. The laboratory tests reported anaemia, leukocytosis, and eosinophilia. We realized a bone marrow aspiration, seric immunoglobulines, abdominal CT scan, parasite detection serology, and coproparasitoscopic evaluation of 3 samples. Finally, we got the diagnosis of larva migrans visceralis due to toxocariasis, because of diffuse hipodense hepatic lesions in abdominal CT scan, and a positive serologic quick test for Toxocara canis (ELISA), after that we started the therapy with albendazol at standard dosage and we obtained excellent response characterized by the abscense of visceromegaly, and the dramatic descense of the eosinophil count. Conclusion. Larva migrans visceralis syndrome is a diagnosis that needs high index of suspicious. In our country, T. canis always has to be considered in the differential diagnosis, because this is one of the main causes of hypereosinophilia, and only early diagnosis could let us start the appropriate treatment for a cure of the disease.

Revue / Journal Title

Boletín Médico del Hospital Infantil de México ISSN 0539-6115 CODEN BMHIAK

Source / Source

2004, vol. 61, n^o3, pp. 228-233 [6 page(s) (article)] (11 ref.)

Langue / Language

Espagnol

Editeur / Publisher

Ediciones Médicas del Hospital Infantil de México Federico Gómez, México, MEXIQUE (1944) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 20051, 35400011211183.0060

Nº notice refdoc (ud4) : 15906993