Titre du document / Document title

The use of a continuous glucose monitoring system in hypoglycemic disorders

Auteur(s) / Author(s)

CONRAD Susan C. ; MASTROTOTARO John J. ; GITELMAN Stephen E. ;

Résumé / Abstract

Objective: To evaluate the use of a continuous glucose monitoring system (CGMS) in the evaluation and treatment of infants and children with hypoglycemic disorders. Methods: Patients with hypoglycemic disorders wore the CGMS device in the Pediatric Clinic Research Center during their evaluation and treatment. Capillary blood glucose (CBG) values were obtained at least 3 times each day and entered into the device for calibration purposes. We evaluated the number of hypoglycemic episodes below 3.3 mmol/l (60 mg/dl) detected by CGMS compared to CBG values and characterized episodes by their duration and intensity. Results: Five patients with hypoglycemic disorders were included in the study. There were a total of 13,369 sensor points, 343 paired sensor and CBG data points, and 57 days included. A total of 180 episodes of hypoglycemia occurred in these five patients, with an average duration of 55 ′ 13 minutes. Using a cut-off of 3.3 mmol/l (60 mg/dl) for hypoglycemia, the sensor had a sensitivity of 65.4%, specificity of 90.6%, and false positive rate of 42.9%. The positive and negative predictive values were 57.1% and 93.2%, respectively. Conclusion: CGMS is a useful adjunct in the diagnosis and evaluation of hypoglycemia, and for documentation of euglycemia in these patients following therapy.

Revue / Journal Title

Journal of pediatric endocrinology & metabolism   ISSN 0334-018X 

Source / Source

2004, vol. 17, n^o3, pp. 281-288 [8 page(s) (article)]

Langue / Language

Anglais

Editeur / Publisher

Freund, Tel Aviv, ISRAEL  (1985) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 20997, 35400011157626.0020