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Titre du document / Document title

Add-on gabapentin in the treatment of opiate withdrawal

Auteur(s) / Author(s)

MARTINEZ-RAGA José ; SABATER Ana ; PEREZ-GALVEZ Bartolome ; CASTELLANO Miguel ; CERVERA Gaspar ;

Résumé / Abstract

Gabapentin is an antiepileptic drug shown to be effective in the treatment of pain disorders and appears to be useful as well for several psychiatric disorders, including bipolar disorder, anxiety disorders, alcohol withdrawal and cocaine dependence. Gabapentin, at a dose of 600 mg three times a day, was evaluated as an add-on medication to a standard detoxification regime in seven heroin dependent individuals undergoing outpatient opiate withdrawal treatment. All seven patients successfully completed opiate detoxification and commenced opiate antagonist treatment with naltrexone on day five of withdrawal treatment, as scheduled. No adverse event was noted. Gabapentin appeared to lead a reduction in symptomatic medication and an overall beneficial effect on symptoms of heroin withdrawal.

Revue / Journal Title

Progress in neuro-psychopharmacology & biological psychiatry    ISSN  0278-5846   CODEN PNPPD7 

Source / Source

2004, vol. 28, no3, pp. 599-601 [3 page(s) (article)]

Langue / Language

Anglais

Editeur / Publisher

Elsevier, Amsterdam, PAYS-BAS  (1982) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 17544, 35400011716181.0210

Nº notice refdoc (ud4) : 15664741



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