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Titre du document / Document title

Cristaluria por ácido ùrico en recién nacidos, su relación con la uricosuria y el pH = Uric acid crystalluria in newborns

Auteur(s) / Author(s)

MEDINA-ESCOBEDO Martha (1) ; VILLANUEVA-JORGE Salha (1) ; CISNEROS-MARTINEZ Elia (1) ; MEDINA-ESCOBEDO Carolina (2) ; GALA-TRUJANO Efrain (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Laboratorio de Investigación, Hospital General Dr. Agustín O'Horán, Secretaría de Salud, Mérida, Yucatán, MEXIQUE
(2) Coordinación Delegacional de Investigación en Salud, Delegación Yucatán, Instituto Mexicano del Seguro Social, Mérida, Yucatán, MEXIQUE

Résumé / Abstract

Introduction. Seric concentration of uric acid, and its urinary excretion is increased in newborns; the aim of this work was to establish the relationship between uric acid crystaluria (UAC), uricosuria (U), and urinary pH (UpH) in a group of newborns. Material and methods. This is a cross sectional, observational study carried on in a second level hospital in Yucatan (a southeast state of Mexico), from March 2001 to February 2002. Healthy newborn, 37 to 42 weeks of gestational age, weighing 2 500 to 4 000 g, of any gender, and fed with breast milk, were included; UAC, U, and UpH were determined. Student's t test, and Spearman test were used in the statistical analysis. Results. From 65 newborn studied, 44 were males; 7 presented UAC, no difference was found when U and UAC were contrasted (1.34 ± 0.92 mg/mg vs 1.54 ± 0.69 mg/mg; P > 0.05) but when compared with UpH a difference was noted (5.5 ± 0.37 vs 6.49 ± 0.78, P < 0.05); no association between UAC and U (rS = -0.08, P > 0.05) was observed; the rS between UAC and UpH was -0.41 (P = 0.001). Conclusion. No association between UAC and uricosuria was observed in our group of newborns; UpH was associated in 16% to UAC; U was higher than those informed by other authors.

Revue / Journal Title

Boletín Médico del Hospital Infantil de México    ISSN  0539-6115   CODEN BMHIAK 

Source / Source

2003, vol. 60, no6, pp. 591-596 [6 page(s) (article)] (16 ref.)

Langue / Language

Espagnol

Editeur / Publisher

Ediciones Médicas del Hospital Infantil de México Federico Gómez, México, MEXIQUE  (1944) (Revue)

Mots-clés anglais / English Keywords

America

;

Central America

;

Human

;

Mexico

;

Urine

;

Uric acid

;

Pediatrics

;

Newborn

;

pH

;

Mots-clés français / French Keywords

Amérique

;

Amérique Centrale

;

Homme

;

Mexique

;

Urine

;

Urique acide

;

Pédiatrie

;

Nouveau né

;

pH

;

Mots-clés espagnols / Spanish Keywords

America

;

America central

;

Hombre

;

Méjico

;

Orina

;

Urico ácido

;

Pediatría

;

Recién nacido

;

pH

;

Mots-clés d'auteur / Author Keywords

Uric acid

;

crystals; uricosuric agents; uricosuria; urinary

;

pH; newborn

;

Localisation / Location

INIST-CNRS, Cote INIST : 20051, 35400011717619.0030

Nº notice refdoc (ud4) : 15643467



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