Titre du document / Document title

Safety and tolerability of azithromycin in pediatric infectious diseases: 2003 update

Auteur(s) / Author(s)

RUUSKANEN Olli ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Pediatrics, Turku University Hospitals, Turku, FINLANDE

Résumé / Abstract

Oral azithromycin suspension has been prescribed to >80 million patients. Children find the color and taste of the oral suspension of azithromycin agreeable, and the drug is well-tolerated. On average 9% of patients have treatment-related adverse events, which are most frequently gastrointestinal complaints. The side effects are mild to moderate and very seldom necessitate withdrawal of the treatment. In addition to the conventional 3-day 10-mg/kg/day regimen and the 10 mglkg on Day 1 followed by 5 mglkg on Days 2 to 5 regimens, single dose 30 mg/kg and 3-day 20-mg/kg/day regimens are well-tolerated, although these new dosages are associated with more adverse effects.

Revue / Journal Title

The Pediatric infectious disease journal   ISSN 0891-3668   CODEN PIDJEV 

Source / Source

2004, vol. 23, n^o 2, SUP (43 p.)  (26 ref.), pp. S135-S139

Langue / Language

Anglais

Editeur / Publisher

Lippincott, Hagerstown, MD, ETATS-UNIS  (1987) (Revue)

Mots-clés anglais / English Keywords

Macrolide ; Human ; Antibiotic ; Antibacterial agent ; Pediatrics ; Child ; Review ; Azithromycin ; Chemotherapy ; Treatment ; Infection ;

Mots-clés français / French Keywords

Macrolide ; Homme ; Antibiotique ; Antibactérien ; Pédiatrie ; Enfant ; Article synthèse ; Azithromycine ; Chimiothérapie ; Traitement ; Infection ;

Mots-clés espagnols / Spanish Keywords

Macrólido ; Hombre ; Antibiótico ; Antibacteriano ; Pediatría ; Niño ; Artículo síntesis ; Azitromicina ; Quimioterapia ; Tratamiento ; Infección ;

Mots-clés d'auteur / Author Keywords

Azithromycin; pediatric; children ; safety ; tolerability ;

Localisation / Location

INIST-CNRS, Cote INIST : 20356, 35400011925469.0060