Titre du document / Document title

Evolution of fungal sex chromosomes

Auteur(s) / Author(s)

FRASER James A. ⁽¹⁾ ; HEITMAN Joseph ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Departments of Molecular Genetics and Microbiology, Medicine, Pharmacology and Cancer Biology Howard Hughes Medical Institute, Duke University Medical Center, Durham, NC 27710, ETATS-UNIS

Résumé / Abstract

Sexual reproduction enables organisms to shuffle two parental genomes to produce recombinant progeny, and to purge the genome of deleterious mutations. Sex is conserved in virtually all organisms, from bacteria and fungi to plants and animals, and yet the mechanisms by which sexual identity are established share both conserved general features and are remarkably diverse. In animals, sexual identity is established by dimorphic sex chromosomes, whereas in fungi a specialized region of the genome, known as the mating-type locus, governs the establishment of cell type Identity and differs in DNA sequence between cells of different mating-types. Recent studies on the mating-type loci of fungi and algae reveal features shared with the mammalian X and Y chromosomes, suggesting that these represent early steps in the evolution of sex chromosomes.

Revue / Journal Title

Molecular microbiology   ISSN 0950-382X 

Source / Source

2004, vol. 51, n^o2, pp. 299-306 [8 page(s) (article)] (1 p.1/4)

Langue / Language

Anglais

Editeur / Publisher

Blackwell Science, Oxford, ROYAUME-UNI  (1987) (Revue)

Mots-clés anglais / English Keywords

Thallophyta ; Microbiology ; Sex chromosome ; Fungi ;

Mots-clés français / French Keywords

Thallophyta ; Microbiologie ; Chromosome sexuel ; Fungi ;

Mots-clés espagnols / Spanish Keywords

Thallophyta ; Microbiología ; Cromosoma sexual ; Fungi ;

Localisation / Location

INIST-CNRS, Cote INIST : 21344, 35400011657005.0010