Titre du document / Document title

Cancer metabolism: facts, fantasy, and fiction

Auteur(s) / Author(s)

XIN LIN ZU ; GUPPY Michael ;

Résumé / Abstract

The concept of a glycolytic cancer cell was introduced by Warburg over 70 years ago. This perception has since become the rationale that drives a considerable proportion of basic research on cancer, and it influences the current strategies for the diagnosis, monitoring, and treatment of cancer. Here we review the data from the last 40 years on this issue. We conclude that there is no evidence that cancer cells are inherently glycolytic, but that some tumours might indeed be glycolytic in vivo as a resuit of their hypoxic environment.

Revue / Journal Title

Biochemical and biophysical research communications    ISSN  0006-291X   CODEN BBRCA9 

Source / Source

2004, vol. 313, n^o3, pp. 459-465 [7 page(s) (article)]

Langue / Language

Anglais

Editeur / Publisher

Elsevier, Amsterdam, PAYS-BAS  (1959) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 8252, 35400011911766.0010