Titre du document / Document title

The performance of a Risk Score as a screening test for undiagnosed hyperglycemia in ethnic minority groups: Data from the 1999 Health Survey for England

Auteur(s) / Author(s)

SPIJKERMAN Annemieke M. W. ⁽¹⁾ ; YUYUN Matthew F. ⁽²⁾ ; GRIFFIN Simon J. ⁽²⁾ ; DEKKER Jacqueline M. ⁽¹⁾ ; NIJPELS Giel ⁽¹⁾ ; WAREHAM Nicholas J. ⁽²⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Institute for Research in Extramural Medicine, VU University Medical Center, Amsterdam, PAYS-BAS
⁽²⁾ Department of Public Health and Primary Care, University of Cambridge, Cambridge, ROYAUME-UNI

Résumé / Abstract

OBJECTIVE- To assess the performance of the Cambridge Risk Score (CRS) to predict undiagnosed hyperglycemia in Caribbean and South Asian people living in the U.K. RESEARCH DESIGN AND METHODS- The CRS uses routinely available data from primary care records to identify people at high risk for undiagnosed type 2 diabetes. The sensitivity, specificity, and area under the receiver operator characteristic (ROC) curve for the CRS cut point of 0.199 were 77, 72, and 80% (95% Cl 68-91), respectively. The risk score was calculated for 248 Caribbean and 555 South Asian participants aged 40-75 years in the 1999 Health Survey for England. Undiagnosed hyperglycemia was considered present if fasting plasma glucose was ≥7.0 mmol/l or HbA_1c was ≥6.5%. Sensitivity, specificity, and predictive values were calculated for various cut points of the risk stoic, and ROC curves were constructed. RESULTS- The area under the ROC curve was 67% (59-76) and 72% (67-78) for Caribbean and South Asians, respectively. The optimal cut point in Caribbean participants was 0.236, sensitivity was 63% (46-77), and specificity was 63% (56-69). In the south Asian population, the optimal cut point was and 0.127, sensitivity was 69% (60-78), and specificity was 64% (60-69). CONCLUSIONS- The CRS, using routinely available data, can be used in a strategy to detect undiagnosed hyperglycemia in Caribbean and South Asian populations. The existence of ethnic group-specific cut points must be further established in future studies.

Revue / Journal Title

Diabetes care   ISSN 0149-5992   CODEN DICAD2 

Source / Source

2004, vol. 27, n^o1, pp. 116-122 [7 page(s) (article)] (38 ref.)

Langue / Language

Anglais

Editeur / Publisher

American Diabetes Association, Alexandria, VA, ETATS-UNIS  (1978) (Revue)

Mots-clés anglais / English Keywords

Endocrinopathy ; Europe ; United Kingdom ; Great Britain ; England ; Survey ; Public health ; Minority ; Ethnic group ; Medical screening ; Score test ; Risk factor ; Diabetes mellitus ; Performance ; Performance evaluation ; Hyperglycemia ;

Mots-clés français / French Keywords

Endocrinopathie ; Europe ; Royaume Uni ; Grande Bretagne ; Angleterre ; Enquête ; Santé publique ; Minorité ; Ethnie ; Dépistage ; Test score ; Facteur risque ; Diabète ; Performance ; Evaluation performance ; Hyperglycémie ;

Mots-clés espagnols / Spanish Keywords

Endocrinopatía ; Europa ; Reino Unido ; Gran Bretaña ; Inglaterra ; Encuesta ; Salud pública ; Minoría ; Etnia ; Descubrimiento ; Factor riesgo ; Diabetes ; Rendimiento ; Evaluación prestación ; Hiperglicemia ;

Localisation / Location

INIST-CNRS, Cote INIST : 18054, 35400011902021.0200