Titre du document / Document title
Hyperglycemia and outcomes from pediatric traumatic brain injury
Auteur(s) / Author(s)
COCHRAN Amalia (1 2) ;
SCAIFE Eric R. (1 3) ;
HANSEN Kristine W. (3) ;
DOWNEY Earl C. (1 3) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Department of Surgery, University of Utah, Salt Lake City, Utah, ETATS-UNIS
(2) Intermountain Injury Control Research Center, University of Utah School of Medicine, Salt Lake City, Utah, ETATS-UNIS
(3) Division of Pediatric Surgery, Primary Children's Medical Center, Salt Lake City, Utah, ETATS-UNIS
Résumé / Abstract
Background: The clinical significance of hyperglycemia after pediatric traumatic brain injury is controversial. This study addresses the relationship between hyperglycemia and outcomes after traumatic brain injury in pediatric patients. Methods: We identified trauma patients admitted during a single year to our regional pediatric referral center with head regional Abbreviated Injury Scale scores ≥ 3. We studied identified patients for admission characteristics potentially influencing their outcomes. The primary outcome measure was Glasgow Outcome Scale score. Results: Patients who died had significantly higher admission serum glucose values than those patients who survived (267 mg/dL vs. 135 mg/dL; p = 0.000). Admission serum glucose ≥ 300 mg/dL was uniformly associated with death. Admission Glasgow Coma Scale score (odds ratio, 0.560; 95% confidence interval, 0.358-0.877) and serum glucose (odds ratio, 1.013; 95% confidence interval, 1.003-1.023) are independent predictors of mortality in children with traumatic head injuries. Conclusion: Hyperglycemia and poor neurologic outcome in head-injured children are associated. The pathophysiology of hyperglycemia in neurologic injury after head trauma remains unclear.
Revue / Journal Title
The Journal of trauma, injury, infection, and critical care
ISSN
1079-6061
Source / Source
2003, vol. 55, n
o6, pp. 1035-1038 [4 page(s) (article)] (14 ref.)
Langue / Language
Anglais
Editeur / Publisher
Lippincott Williams & Wilkins, Hagerstown, MD, ETATS-UNIS
(1995)
(Revue)
Mots-clés anglais / English Keywords
;
;
;
;
;
;
;
;
;
;
;
;
;
;
Mots-clés français / French Keywords
;
;
;
;
;
;
;
;
;
;
;
;
;
;
Mots-clés espagnols / Spanish Keywords
;
;
;
;
;
;
;
;
;
;
;
;
;
;
Mots-clés d'auteur / Author Keywords
;
;
;
;
Localisation / Location
INIST-CNRS, Cote INIST : 507, 35400011897312.0040
Nº notice refdoc (ud4) : 15370417
