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Titre du document / Document title

Psyllium-associated anaphylaxis and death: a case report and review of the literature

Auteur(s) / Author(s)

KHALILI Barzin (1) ; BARDANA Emil J. (1) ; YUNGINGER John W. (2) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Oregon Health & Sciences University, Portland, Oregon, ETATS-UNIS
(2) Mayo Clinic, Rochester, Minnesota, ETATS-UNIS

Résumé / Abstract

Background: Psyllium use has increased significantly in the United States in part due to its lipid-lowering property. The increased prevalence of consumption has led to its recognition as an emerging food allergen. Objectives: To report the case of a 42-year-old woman who experienced fatal anaphylaxis after ingesting a psyllium-based product and to review the literature. Methods: The MEDLINE database was searched for articles from 1966 to 2002 using the keywords psyllium or ispaghula and each of the following: allergy, hypersensitivity, anaphylaxis, and asthma. Both English and non-English articles were included. Results: Psyllium hypersensitivity has been well described in health care workers and pharmaceutical plant employees. Clinical manifestations of allergy range from upper respiratory tract symptoms on inhalation to anaphylaxis on ingestion. The prevalence of sensitization varies between these 2 groups. The allergenic epitope is not known. Conclusions: We present a case of psyllium hypersensitivity that resulted in death. There is a clear association between atopy and psyllium allergy. The case underscores the fact that even nonprescription natural products can be harmful to people with allergies.

Revue / Journal Title

Annals of allergy, asthma, & immunology    ISSN  1081-1206 

Source / Source

2003, vol. 91, no6, pp. 579-584 [6 page(s) (article)] (50 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, New York, NY, ETATS-UNIS  (1995) (Revue)

Mots-clés anglais / English Keywords

Immunopathology

;

Bibliographic review

;

Allergen

;

Death

;

Case study

;

Allergy

;

Female

;

Human

;

Anaphylaxis

;

Mots-clés français / French Keywords

Immunopathologie

;

Psyllium

;

Revue bibliographique

;

Allergène

;

Mort

;

Etude cas

;

Allergie

;

Femelle

;

Homme

;

Anaphylaxie

;

Mots-clés espagnols / Spanish Keywords

Inmunopatología

;

Revista bibliográfica

;

Alergeno

;

Muerte

;

Estudio caso

;

Alergia

;

Hembra

;

Hombre

;

Anafilaxia

;

Localisation / Location

INIST-CNRS, Cote INIST : 5910, 35400011896447.0150

Nº notice refdoc (ud4) : 15363332



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