Titre du document / Document title

Metoclopramide and unintended weight gain

Auteur(s) / Author(s)

SANSONE Randy A. ^{(1 2)} ; SANSONE Lori A. ⁽³⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Psychiatry, Wright State University School of Medicine, Dayton, Ohio, ETATS-UNIS
⁽²⁾ Department of Internal Medicine, Wright State University School of Medicine, Dayton, Ohio, ETATS-UNIS
⁽³⁾ Private practice (family medicine), Bellbrook, Ohio, ETATS-UNIS

Résumé / Abstract

Objective: This paper describes the case of a 19-year-old female with anorexia nervosa (restricting type) who was prescribed metoclopramide (Reglan, Robins, Richmond, VA) for delayed gastric emptying. She subsequently experienced dramatic and unintended weight gain. Results: The initial treatment of delayed gastric emptying with metoclopramide did not result in a significant change in body weight. However, an increase in the dose resulted in a 20% increase in the patient's body weight over a 2-month period. Discussion: The risks of weight gain that accompany the administration of metoclopramide are discussed, as well as the postulated etiology and psychological implications for the patient.

Revue / Journal Title

The International journal of eating disorders   ISSN 0276-3478   CODEN INDIDJ 

Source / Source

2003, vol. 34, n^o2, pp. 265-268 [4 page(s) (article)] (16 ref.)

Langue / Language

Anglais

Editeur / Publisher

Wiley, New York, NY, ETATS-UNIS  (1981) (Revue)

Mots-clés anglais / English Keywords

Eating disorder ; Human ; Benzamide derivatives ; Young adult ; Female ; Case study ; Weight gain ; Toxicity ; Dose activity relation ; Dopamine antagonist ; D2 Dopamine receptor ; Antagonist ; Antiemetic ; Metoclopramide ; Chemotherapy ; Gastric emptying ; Delay ; Symptomatology ; Treatment ; Anorexia nervosa ;

Mots-clés français / French Keywords

Trouble comportement alimentaire ; Homme ; Benzamide dérivé ; Adulte jeune ; Femelle ; Etude cas ; Prise poids ; Toxicité ; Relation dose réponse ; Antagoniste dopamine ; Récepteur dopaminergique D2 ; Antagoniste ; Antiémétique ; Métoclopramide ; Chimiothérapie ; Evacuation gastrique ; Retard ; Symptomatologie ; Traitement ; Anorexie mentale ;

Mots-clés espagnols / Spanish Keywords

Trastorno conducta alimentaria ; Hombre ; Benzamida derivado ; Adulto joven ; Hembra ; Estudio caso ; Ganancia peso ; Toxicidad ; Relación dosis respuesta ; Antagonista dopamina ; Receptor dopaminérgico D2 ; Antagonista ; Antiemético ; Metoclopramida ; Quimioterapia ; Vaciamiento gástrico ; Retraso ; Sintomatología ; Tratamiento ; Anorexia mental ;

Localisation / Location

INIST-CNRS, Cote INIST : 20136, 35400011233104.0100