Titre du document / Document title

Making progress in stable patients post stroke or transient ischaemic attack: Implications for general practice

Auteur(s) / Author(s)

JACKSON G. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Cardiothoracic Centre, St Thomas'Hospital, London, ROYAUME-UNI

Résumé / Abstract

Stroke is a major cause of morbidity and mortality. Those who survive have a one in six chance of a further stroke in the ensuing five years. The perindopril protection against recurrent stroke study (PROGRESS) is the first specific trial to address whether blood pressure lowering in hypertensive or non-hypertensive patients with a history of stroke or transient ischaemic attack (TIA) would reduce subsequent cerebrovascular and cardiovascular events. Results show that treatment based on perindopril significantly reduces stroke (28%), cardiovascular events (26%) and heart failure (26%). Stable patients post stroke should be considered for perindopril, and indapamide if possible, along with other evidence based risk reduction treatments (e.g. aspirin, statins). Therapy can be initiated and monitored either from hospital outpatients or general practice or both in co-operation.

Revue / Journal Title

International journal of clinical practice   ISSN 1368-5031 

Source / Source

2003, vol. 57, n^o5, pp. 385-387 [3 page(s) (article)] (19 ref.)

Langue / Language

Anglais

Editeur / Publisher

Blackwell, Oxford, ROYAUME-UNI  (1997) (Revue)

Mots-clés anglais / English Keywords

Diuretic ; Antihypertensive agent ; ACE inhibitor ; Myocardial disease ; Coronary heart disease ; Vascular disease ; Cardiovascular disease ; Cerebrovascular disease ; Cerebral disorder ; Central nervous system disease ; Nervous system diseases ; Hypertension ; Arterial pressure ; Treatment efficiency ; Indapamide ; Follow up study ; Ramipril ; Perindopril ; Heart failure ; Myocardium ; Infarct ; Relapse ; Treatment ; Chemotherapy ; Human ; Transitory ; Stroke ;

Mots-clés français / French Keywords

Diurétique ; Antihypertenseur ; Inhibiteur angiotensin converting enzyme ; Myocarde pathologie ; Cardiopathie coronaire ; Vaisseau sanguin pathologie ; Appareil circulatoire pathologie ; Cérébrovasculaire pathologie ; Encéphale pathologie ; Système nerveux central pathologie ; Système nerveux pathologie ; Hypertension artérielle ; Pression artérielle ; Efficacité traitement ; Indapamide ; Etude longitudinale ; Ramipril ; Périndopril ; Insuffisance cardiaque ; Myocarde ; Infarctus ; Récidive ; Traitement ; Chimiothérapie ; Homme ; Transitoire ; Accident cérébrovasculaire ;

Mots-clés espagnols / Spanish Keywords

Diurético ; Antihipertensivo ; Inhibidor angiotensin converting enzyme ; Miocardio patología ; Cardiopatía coronaria ; Vaso sanguíneo patología ; Aparato circulatorio patología ; Vaso sanguíneo encéfalo patología ; Encéfalo patología ; Sistema nervosio central patología ; Sistema nervioso patología ; Hipertensión arterial ; Presión arterial ; Eficacia tratamiento ; Indapamida ; Estudio longitudinal ; Ramipril ; Perindopril ; Insuficiencia cardíaca ; Miocardio ; Infarto ; Recaida ; Tratamiento ; Quimioterapia ; Hombre ; Transitorio ; Accidente cerebrovascular ;

Localisation / Location

INIST-CNRS, Cote INIST : 15561, 35400011130805.0080