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Titre du document / Document title

Survival rates with uveal melanoma in the United States: 1973-1997

Auteur(s) / Author(s)

SINGH Arun D. (1) ; TOPHAM Allan (2) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania, ETATS-UNIS
(2) Oncology Data Services, Thomas Jefferson University, Philadelphia, Pennsylvania, ETATS-UNIS

Résumé / Abstract

Purpose: To determine variations in 5-year relative survival rates with primary uveal melanoma in the United States over a 25-year period from 1973 to 1997. Design: Systematic review of existing databases. Participants: Two thousand four hundred ninety-three patients with primary uveal melanoma, International Classification of Oncology [ICDO-2] codes C69.3 [choroid melanoma] and C69.4 [ciliary body and iris]) derived from Surveillance, Epidemiology, and End Results (SEER) program database in the United States from 1973 to 1997. Methods: The patients were stratified according to the treatment (surgery or radiotherapy). The relative 5-year survival was calculated for 2054 patients diagnosed between 1973 and 1993 by the life table method using US life expectancy tables. Main Outcome Measures: The relative 5-year survival rate. Results: Surgical treatment was performed in 1476 (72%) cases, and radiotherapy was given in 300 (15%) cases. The proportion of cases treated by radiotherapy increased progressively from 2% to 28% in 20 years. Relative 5-year survival rates ranged from 77% to 84% without a statistically significant variation. Conclusions: Advances made in the local methods of treatment of primary uveal melanoma have not led to an improvement in survival. Systemic approaches to management of uveal melanoma are warranted.

Revue / Journal Title

Ophthalmology    ISSN  0161-6420   CODEN OPHTDG 

Source / Source

2003, vol. 110, no5, pp. 962-965 [4 page(s) (article)] (26 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, New York, NY, ETATS-UNIS  (1976) (Revue)

Mots-clés anglais / English Keywords

Uvea disease

;

Malignant tumor

;

Eye disease

;

America

;

North America

;

United States

;

Uvea

;

Rate

;

Survival

;

Malignant melanoma

;

Human

;

Mots-clés français / French Keywords

Uvée pathologie

;

Tumeur maligne

;

Oeil pathologie

;

Amérique

;

Amérique du Nord

;

Etats Unis

;

Uvée

;

Taux

;

Survie

;

Mélanome malin

;

Homme

;

Mots-clés espagnols / Spanish Keywords

Uvea patología

;

Tumor maligno

;

Ojo patología

;

America

;

America del norte

;

Estados Unidos

;

Uvea

;

Tasa

;

Sobrevivencia

;

Melanoma maligno

;

Hombre

;

Localisation / Location

INIST-CNRS, Cote INIST : 18914, 35400011817997.0200

Nº notice refdoc (ud4) : 14795057



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