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Titre du document / Document title

Pulmonary function in fur-processing workers: A dose-response relationship

Auteur(s) / Author(s)

JIE CHEN (1) ; JIEZHI LOU (1) ; ZHENLIN LIU (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Division of Pneumoconiosis, School of Public Health, China Medical University, Shenyang, CHINE

Résumé / Abstract

Pulmonary function tests were conducted in 212 male workers exposed to fur dust in a fur-processing factory, and in 148 unexposed male workers. The authors used the cumulative dose of dust exposure (mg-yr) as an exposure index to relate to pulmonary function injury, as measured by pulmonary function tests, in exposed workers. The results showed that fur workers had lower percentages of predicted pulmonary function, as measured by forced vital capacity (FVC), forced expiratory volume in 1 sec (FEV1.0), and maximal flow rate of expiration at 50% and 25% of forced vital capacity (V50 and V25, respectively), compared with controls (p < 0.01). As the cumulative dose of fur dust exposure increased, average levels of pulmonary function declined significantly (p < 0.01), and pulmonary function abnormalities (i.e., < 80% of predicted FVC and FEV1.0, or < 70% of predicted V50 and V25) increased significantly (p < 0.05). Multiple-regression results identified fur dust exposure as the leading risk factor associated with the decline in pulmonary function in the exposed group. The results demonstrated a dose-response relationship between fur dust exposure and respiratory system injury, as measured by pulmonary function tests in fur-processing workers. On the basis of this dose-response relationship and the use of life-tables, the authors proposed an exposure limit of 4 mg/m3 for fur dust.

Revue / Journal Title

Archives of environmental health    ISSN  0003-9896   CODEN AEHLAU 

Source / Source

2003, vol. 58, no1, pp. 37-41 [5 page(s) (article)] (8 ref.)

Langue / Language

Anglais

Editeur / Publisher

Heldref, Washington, DC, ETATS-UNIS  (1960-2004) (Revue)

Mots-clés anglais / English Keywords

Ambient air concentration

;

Maximum permissible concentration

;

Work place

;

Dose activity relation

;

Lung function

;

Occupational medicine

;

Occupational exposure

;

Human

;

Toxicity

;

Textile industry

;

Fur

;

Dust

;

Mots-clés français / French Keywords

Teneur air ambiant

;

Concentration maximale admissible

;

Lieu travail

;

Relation dose réponse

;

Fonction respiratoire

;

Médecine travail

;

Exposition professionnelle

;

Homme

;

Toxicité

;

Industrie textile

;

Fourrure

;

Poussière

;

Mots-clés espagnols / Spanish Keywords

Contenido aire ambiental

;

Concentración máxima admisible

;

Lugar trabajo

;

Relación dosis respuesta

;

Función respiratoria

;

Medicina ocupacional

;

Exposición profesional

;

Hombre

;

Toxicidad

;

Industria textil

;

Piel animal

;

Polvo

;

Localisation / Location

INIST-CNRS, Cote INIST : 2784, 35400011801934.0050

Nº notice refdoc (ud4) : 14777753



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