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Titre du document / Document title

A randomized controlled trial of auricular acupuncture for cocaine dependence

Auteur(s) / Author(s)

AVANTS S. K. (1) ; MARGOLIN A. (1) ; HOLFORD T. R. (2) ; KOSTEN T. R. (1 3) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Division of Substance Abuse, Department of Psychiatry Yale University School of Medicine, New Haven, ETATS-UNIS
(2) Division of Biostatistics, School of Epidemiology and Public Health, Yale University School of Medicine, New Haven, ETATS-UNIS
(3) Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, New Haven, ETATS-UNIS

Résumé / Abstract

Background: Partly because of a lack of a conventional, effective treatment for cocaine addiction, auricular acupuncture is used to treat this disorder in numerous drug treatment facilities across the country for both primary cocaine-dependent and opiate-dependent populations. Objective: To evaluate the effectiveness of auricular acupuncture for the treatment of cocaine addiction. Methods: Eighty-two cocaine-dependent, methadone-maintained patients were randomly assigned to 1 of 3 conditions: auricular acupuncture, a needle-insertion control condition, or a no-needle relaxation control. Treatment sessions were provided 5 times weekly for 8 weeks. The primary outcome was cocaine use assessed by 3-times-weekly urine toxicology screens. Results: Longitudinal analysis of the urine data for the intent-to-treat sample showed that patients assigned to acupuncture were significantly more likely to provide cocaine-negative urine samples relative to both the relaxation control (odds ratio, 3.41; 95% confidence interval, 1.33-8.72; P=.01) and the needle-insertion control (odds ratio, 2.40; 95% confidence interval, 1.00-5.75; P=.05). Conclusions: Findings from the current study suggest that acupuncture shows promise for the treatment of cocaine dependence. Further investigation of this treatment modality appears to be warranted.

Revue / Journal Title

Archives of internal medicine    ISSN  0003-9926   CODEN AIMDAP 

Source / Source

2000, vol. 160, no15, pp. 2305-2312 (43 ref.)

Langue / Language

Anglais

Editeur / Publisher

American Medical Association, Chicago, IL, ETATS-UNIS  (1960-2012) (Revue)

Mots-clés anglais / English Keywords

Consumption

;

Drug of abuse

;

Cocaine

;

Weaning

;

Acupuncture

;

Auriculotherapy

;

Clinical trial

;

Randomization

;

Human

;

Drug addiction

;

Oriental medicine

;

Folk medicine

;

Mots-clés français / French Keywords

Consommation

;

Substance toxicomanogène

;

Cocaïne

;

Sevrage

;

Acupuncture

;

Auriculothérapie

;

Essai clinique

;

Randomisation

;

Homme

;

Toxicomanie

;

Médecine orientale

;

Médecine traditionnelle

;

Mots-clés espagnols / Spanish Keywords

Consumo

;

Sustancia toxicomanógena

;

Cocaína

;

Destete

;

Acupuntura

;

Auriculoterapia

;

Ensayo clínico

;

Aleatorización

;

Hombre

;

Toxicomanía

;

Medicina oriental

;

Medicina tradicional

;

Localisation / Location

INIST-CNRS, Cote INIST : 2040, 35400009125361.0080

Nº notice refdoc (ud4) : 1474370



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