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Titre du document / Document title

Trattamento con autovaccino delle osteomieliti croniche = Treatment of chronic osteomyelitis by autovaccine

Auteur(s) / Author(s)

DE VITO D. ; MASTRORILLO G. ; RIZZO G. ;

Résumé / Abstract

Osteomyelitis, generally caused by Staphylococcus spp., is unresponsive to antimicrobial therapy in many people. Therefore interest is turning towards therapy by stimulation of the immune defence mechanism with autovaccine formed by aetiological agents responsible for osteomyelitis. We report on the effect of vaccinotherapy in 82 patients affected by chronic osteomyelitis with follow-up of 2-4 years. In 54% of the patients there was a clinical and radiological recovery, whereas in 46% recovery was possible only after an operation. The immune parameters at different time intervals following the immunotherapeutical regimen were evaluated in 16 patients with chronic osteomyelitis, 13 of whom had a depressed immune response. The autogenous vaccine was able to increase Ig production, while there was no effect on the former immune parameters.

Revue / Journal Title

L' Igiene moderna    ISSN  0019-1655 

Source / Source

2002, vol. 118, no4, pp. 267-274 [8 page(s) (article)]

Langue / Language

Italien
Revue : Multilingue

Editeur / Publisher

Igiene moderna, Roma, ITALIE  (1908) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 3942, 35400010940675.0030

Nº notice refdoc (ud4) : 14605070



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