Titre du document / Document title
O-demethylation and sulfation of 7-methoxylated flavanones by Cunninghamella elegans
Auteur(s) / Author(s)
IBRAHIM Abdel-Rahim Sayed (1) ;
GALAL Ahmed Mohamed (2) ;
AHMED Mohammed Shamim (3) ;
MOSSA Gabir Salem (3) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Pharmacognosy Departments, College of Pharmacy, Tanta University, Tanta 8130, EGYPTE
(2) College of Pharmacy, Cairo University, Cairo 11562, EGYPTE
(3) College of Pharmacy, King Saud University, Riyadh 11451, ARABIE SAOUDITE
Résumé / Abstract
Metabolism of 7-O-methylnaringenin (sakuranetin) by Cunninghamella elegans NRRL 1392 yielded naringenin and naringenin-4'-sulfate. C. elegans also converted 5,3',4'-trihydroxy-7-methoxyflavanone into eriodictyol-4'-sulfate. Furthermore, incubation of 5,4'-dihydroxy-7,3'-dimethoxyflavanone with the same fungus gave homoeriodictyol (5,7,4'-trihydroxy-3'-methoxyflavanone) and homoeriodicytol-7-sulfate. The structures of the new metabolites were established by spectral analysis including 2D-NMR, HR-ESI-FT-MS beside hydrolysis by acid.
Revue / Journal Title
Chemical and pharmaceutical bulletin
ISSN
0009-2363
CODEN CPBTAL
Source / Source
2003, vol. 51, n
o2, pp. 203-206 [4 page(s) (article)] (24 ref.)
Langue / Language
Anglais
Editeur / Publisher
JAACC, Tokyo, JAPON
(1958)
(Revue)
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Localisation / Location
INIST-CNRS, Cote INIST : 4123, 35400010939602.0180
Nº notice refdoc (ud4) : 14569933
