Titre du document / Document title
Acute renal failure = Insuffisance rénale aiguë
Auteur(s) / Author(s)
GLYNNE Paul A. (1) ;
LIGHTSTONE Liz (1) ;
Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)
(1) Renal Section, Division of Medicine, Imperial College School of Medicine, Hammersmith Hospital, London, ROYAUME-UNI
Résumé / Abstract
Acute renal failure (ARF) is usually associated with oliguria (urine output <400 ml/day), increased plasma urea, creatinine and potassium concentrations, acidosis, and ultimately fluid overload In-hospital ARF is most commonly caused by acute tubule necrosis resulting from multiple nephrotoxic insults such as hypotension, sepsis and nephrotoxic drugs In at-risk patients (elderly, diabetics and those with vascular disease, particularly after exposure to angiotensin-converting enzyme inhibitors or radiocontrast), optimise intravascular volume and avoid nephrotoxic drugs Discuss all cases of ARF with a nephrologist Exclude urinary tract obstruction in all patients presenting with ARF Early recognition of rapidly progressive glomerulonephritis (haematuria, urinary red cell casts and features of systemic inflammation), an important cause of ARF developing outside hospital, is crucial since early treatment may prevent the development of end-stage renal failure In established ARF, the immediate priority is to make the patient safe by treating hyperkalaemia and fluid overload Urgent dialysis is indicated in the presence of severe, refractory hyperkalaemia, profound metabolic acidosis, pulmonary oedema and severe uraemia (encephalopathy, pericarditis or bleeding).
Revue / Journal Title
Clinical medicine
ISSN
1470-2118
Source / Source
2001, vol. 1, n
o4, pp. 266-273 (19 ref.)
Langue / Language
Anglais
Editeur / Publisher
Royal College of Physicians, London, ROYAUME-UNI
(2001)
(Revue)
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Localisation / Location
INIST-CNRS, Cote INIST : 13339, 35400009582116.0010
Nº notice refdoc (ud4) : 14215524