Titre du document / Document title

Bilateral central serous chorioretinopathy in a patient treated with systemic cortico-steroids for non-Hodgkin lymphoma

Auteur(s) / Author(s)

BANDELLO F. ^{(1 2)} ; INCORVAIA C. ⁽¹⁾ ; ROSA N. ⁽³⁾ ; PARMEGGIANI F. ⁽¹⁾ ; COSTAGLIOLA C. ⁽¹⁾ ; SEBASTIANI A. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Ophthalmology, University of Ferrara, Ferrara, ITALIE
⁽²⁾ Department of Ophthalmology, University of Udine, Udine, ITALIE
⁽³⁾ Department of Ophthalmology, II University of Naples, Naples, ITALIE

Résumé / Abstract

PURPOSE. To describe the concomitant occurrence of systemic cortico-steroid treatment and the development of bilateral central serous chorioretinopathy (CSC), which promptly regressed after the reduction of the drug dosage, up to its scheduled withdrawal. METHODS. Case report. RESULTS. A 46-year-old white male, with a history of monolateral CSC, had a non-Hodgkin lymphoma on his right cheek. Soon after surgical excision of the tumoral lesion, he received a standard post-operative regimen of decreasing intramuscular betamethasone for 25 days, followed by 10 day's withdrawal, then cycles of intravenous cyclophosphamide and vincristine, followed by 7-day oral prednisone, repeated monthly for three months. Fluorescein angiographies at the end of the first oral cortico-steroid cycle and before starting the second, documented the occurrence of bilateral CSC and its regression, which were chronologically related respectively to the cortico-steroid administration and withdrawal. CONCLUSIONS. This case further demonstrates that systemic cortico-steroids can be responsible for the occurrence of CSC. The patient's history should always be checked for any previous CSC episodes. In these subjects, periodical ophthalmoscopic examination is essential to discover early or asymptomatic steroid-related CSC patterns, to prevent complications of the disease.

Revue / Journal Title

European Journal of Ophthalmology   ISSN 1120-6721 

Source / Source

2002, vol. 12, n^o2, pp. 123-126 (16 ref.)

Langue / Language

Anglais

Editeur / Publisher

Wichtig, Milano, ITALIE  (1991) (Revue)

Mots-clés anglais / English Keywords

Uvea disease ; Retinopathy ; Eye disease ; Lymphoproliferative syndrome ; Malignant hemopathy ; Human ; Case study ; Toxicity ; Systemic route ; Treatment ; Chemotherapy ; Corticosteroid ; Bilateral ; Central serous chorioretinopathy ; Non Hodgkin lymphoma ;

Mots-clés français / French Keywords

Uvée pathologie ; Rétinopathie ; Oeil pathologie ; Lymphoprolifératif syndrome ; Hémopathie maligne ; Homme ; Etude cas ; Toxicité ; Voie générale ; Traitement ; Chimiothérapie ; Corticostéroïde ; Bilatéral ; Choriorétinite séreuse centrale ; Lymphome non hodgkinien ;

Mots-clés espagnols / Spanish Keywords

Uvea patología ; Retinopatía ; Ojo patología ; Linfoproliferativo síndrome ; Hemopatía maligna ; Hombre ; Estudio caso ; Toxicidad ; Vía general ; Tratamiento ; Quimioterapia ; Corticoesteroide ; Bilateral ; Coriorretinitis serosa central ; Linfoma no Hodgkin ;

Localisation / Location

INIST-CNRS, Cote INIST : 22516, 35400010106848.0080