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Titre du document / Document title

Survival of patients with untreated breast cancer

Auteur(s) / Author(s)

JOHNSTONE P. A. S. (1 2) ; NORTON M. S. (3) ; RIFFENBURGH R. H. (4) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Division of Radiation Oncology, Naval Medical Center San Diego, San Diego, California, ETATS-UNIS
(2) Division of Radiation Oncology, University of California, San Diego, California, ETATS-UNIS
(3) Division of Medical Oncology, Naval Medical Center San Diego, San Diego, California, ETATS-UNIS
(4) Department of Clinical Research, Naval Medical Center San Diego, San Diego, California, ETATS-UNIS

Résumé / Abstract

Knowing the clinical prognosis of untreated breast cancer is useful in dealing with patients with neglected disease or in environments with poorly developed healthcare systems. This study analyzes historical survival data in two sets of untreated patients: (1) 250 patients followed until death (up to 12 years) for which autopsy results are available and (2) an amalgam of 1,022 patients from several papers. Data from nine published papers underwent actuarial analysis. Median survival time of the 250 patients followed to death was 2.7 years. Actuarial 5- and 10-year survival rates for these patients with untreated breast cancer was 18.4% and 3.6%, respectively. For the amalgamated 1,022 patients, median survival time was 2.3 years. Actuarial 5- and (partially fitted) 10-year survival rates for these patients with untreated breast cancer was 19.8% and 3.7%, respectively. Historical data of untreated breast cancer patients reveal a potential for long survival in some cases. The spectrum of clinical aggressiveness of breast cancer varies between virulence and chronic disease.

Revue / Journal Title

Journal of surgical oncology    ISSN  0022-4790   CODEN JSONAU 

Source / Source

2000, vol. 73, no4, pp. 273-277 (13 ref.)

Langue / Language

Anglais

Editeur / Publisher

Wiley-Liss, New York, NY, ETATS-UNIS  (1969) (Revue)

Mots-clés anglais / English Keywords

Malignant tumor

;

Mammary gland

;

Female

;

Human

;

Unresectable

;

Survival curve

;

Prognosis

;

Long term

;

Medium term

;

Statistical analysis

;

Cohort study

;

Mammary gland diseases

;

Mots-clés français / French Keywords

Tumeur maligne

;

Glande mammaire

;

Femelle

;

Homme

;

Inopérable

;

Courbe survie

;

Pronostic

;

Long terme

;

Moyen terme

;

Analyse statistique

;

Etude cohorte

;

Glande mammaire pathologie

;

Mots-clés espagnols / Spanish Keywords

Tumor maligno

;

Glándula mamaria

;

Hembra

;

Hombre

;

Inoperable

;

Curva sobrevivencia

;

Pronóstico

;

Largo plazo

;

Término medio

;

Análisis estadístico

;

Estudio cohorte

;

Glándula mamaria patología

;

Localisation / Location

INIST-CNRS, Cote INIST : 14855, 35400008237498.0150

Nº notice refdoc (ud4) : 1352900



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