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Titre du document / Document title

Antibacterial activity of ozonized sunflower oil, Oleozón, against Staphylococcus aureus and Staphylococcus epidermidis

Auteur(s) / Author(s)

LEZCANO I. (1) ; NUNEZ N. (1) ; ESPINO M. (2) ; GOMEZ M. (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) Ozone Research Center. National Center for Scientific Research, P. O. Box. 6880, Havana, CUBA
(2) Gynecological and Obstetric America Arias Hospital, Havana, CUBA

Résumé / Abstract

Ozonized sunflower oil, Oleozón, has shown antimicrobial effects against several bacterial species. The purpose of this paper was to study in vitro activity of ozonized sunflower oil, Oleozón, on Staphylococcus aureus and Staphylococcus epidermidis, methicillin susceptible and methicillin resistant strains. Minimal Inhibitory Concentrations (MICs) and Minimal Bactericidal Concentrations (MBCs) were determined based on National Committee for Clinical Laboratory Standards (NCCLS) guidelines. Meanwhile, kinetic studies were performed. Oleozón was effective against all strains, MIC90 was 9.5 mg/mL and MBC90 was 356 mg/mL. First order inactivation kinetics with respect to bacterial concentrations were found. The longest time necessary to obtain the total inactivation was 60 minutes for methicillin susceptible strains and 180 minutes for methicillin resistant strains.

Revue / Journal Title

Ozone : science & engineering    ISSN  0191-9512   CODEN OZSEDS 

Source / Source

2000, vol. 22, no2, pp. 207-214 (16 ref.)

Langue / Language

Anglais

Editeur / Publisher

Taylor & Francis, Philadelphia, PA, ETATS-UNIS  (1979) (Revue)

Mots-clés anglais / English Keywords

Sunflower oil

;

Ozonization

;

Antibacterial agent

;

Biological activity

;

In vitro

;

Staphylococcus aureus

;

Minimum inhibitory concentration

;

Staphylococcus epidermidis

;

Kinetics

;

Sensitivity resistance

;

Minimum bactericidal concentration

;

Micrococcaceae

;

Micrococcales

;

Bacteria

;

Mots-clés français / French Keywords

Huile tournesol

;

Ozonation

;

Antibactérien

;

Activité biologique

;

In vitro

;

Staphylococcus aureus

;

Concentration minimale inhibitrice

;

Staphylococcus epidermidis

;

Cinétique

;

Sensibilité résistance

;

Concentration minimale bactéricide

;

Micrococcaceae

;

Micrococcales

;

Bactérie

;

Mots-clés espagnols / Spanish Keywords

Aceite girasol

;

Ozonización

;

Antibacteriano

;

Actividad biológica

;

In vitro

;

Staphylococcus aureus

;

Concentración mínima inhibidora

;

Staphylococcus epidermidis

;

Cinética

;

Sensibilidad resistencia

;

Concentración mínima bactericida

;

Micrococcaceae

;

Micrococcales

;

Bacteria

;

Localisation / Location

INIST-CNRS, Cote INIST : 18256, 35400008734247.0070

Nº notice refdoc (ud4) : 1348379



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