Titre du document / Document title

Serum concentration of free T³, free T⁴ and TSH in healthy children

Auteur(s) / Author(s)

CIOFFI Michele ; GAZZERRO Patrizia ; VIETRI Maria Teresa ; MAGNETTA Rosa ; DURANTE Adriana ; D'AURIA Annamaria ; PUCA Giovanni Alfredo ; MOLINARI Anna Maria ;

Résumé / Abstract

Objective: It is rare that manufacturers report age-related FT³, FT⁴ and TSH normal ranges in healthy children. Study design: Using a solid phase time-resolved fluoroimmunometric method, we determined serum FT³, FT⁴ and TSH in 3,360 healthy children, age 2-16 years, that we grouped into two age ranges (2-7 yr and 9-16 yr). Results: Boys' and girls' mean serum thyroid hormone values substantially overlap in all age groups. In the age range 2-7 yr, FT³, FT⁴ and TSH values were 0.10-0.67 ng/dl (mean 0.37 ng/dl), range 0.45-2.29 ng/dl (mean 1.18 ng/dl) and 0.10-5.9 μU/ml (mean 2.2 pU/ml), respectively. In the age range 9-16 yr, FT³, FT⁴ and TSH values were 0.11-0.53 ng/dl (mean 0.35 ng/dl), 0.69-1.69 ng/dl (mean 1.07 ng/dl) and 0.20-6.1 pU/ml (mean 2.3 μU/ml), respectively. Conclusion: Our results represent a useful set of reference values in children and can help physicians in the management of thyroid diseases.

Revue / Journal Title

Journal of pediatric endocrinology & metabolism    ISSN  0334-018X 

Source / Source

2001, vol. 14, n^o9, pp. 1635-1639 [5 page(s) (article)]

Langue / Language

Anglais

Editeur / Publisher

Freund, Tel Aviv, ISRAEL  (1985) (Revue)

Localisation / Location

INIST-CNRS, Cote INIST : 20997, 35400009468902.0050