Titre du document / Document title

Protein meals reduce nausea and gastric slow wave dysrhythmic activity in first trimester pregnancy

Auteur(s) / Author(s)

JEDNAK M. A. ⁽¹⁾ ; SHADIGIAN E. M. ⁽²⁾ ; KIM M. S. ⁽¹⁾ ; WOODS M. L. ⁽¹⁾ ; HOOPER F. G. ⁽¹⁾ ; OWYANG C. ⁽¹⁾ ; HASLER W. L. ⁽¹⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Internal Medicine, Division of Gastroenterology, Ann Arbor, Michigan 48109, ETATS-UNIS
⁽²⁾ Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, ETATS-UNIS

Résumé / Abstract

First trimester nausea is associated with gastric slow wave dysrhythmias (tachygastria, bradygastria). We tested the roles of meal composition and caloric content on nausea and slow wave rhythm in 14 nauseated pregnant women. Electrogastrography quantified dysrhythmic activity and signal power responses to meals. Symptomatic women reported mild to moderate nausea and exhibited increased dysrhythmias during fasting (P < 0.05). Protein-predominant meals reduced nausea and dysrhythmic activity to greater degrees than equicaloric carbohydrate and fat meals and noncaloric meals (P < 0.05). Meal consistency did not affect symptom responses, although liquid meals decreased dysrhythmias more than solids (P < 0.05). Carbohydrates and fats increased electrogastrographic power to similar degrees as proteins, whereas responses to noncaloric meals were less. In conclusion, protein meals selectively reduce nausea and gastric slow wave dysrhythmias in first trimester pregnancy. Meal consistency is a limited factor in the favorable effects of protein. Electrogastrographic power changes do not explain the symptom response to protein. Thus dietary modulation of gastric myoelectric rhythm with protein supplementation may provide symptomatic benefit in nausea of pregnancy.

Revue / Journal Title

American journal of physiology. Gastrointestinal and liver physiology   ISSN 0193-1857   CODEN APGPDF 

Source / Source

1999, vol. 40, n^o4, pp. G855-G861 (30 ref.)

Langue / Language

Anglais

Editeur / Publisher

American Physiological Society, Bethesda, MD, ETATS-UNIS  (1980) (Revue)

Mots-clés anglais / English Keywords

First trimester ; Pregnancy ; Protein content ; Meal ; Supplemented diet ; Motility ; Gastric emptying ; Vomiting ; Nausea ; Dysfunction ; Rhythm ; Stomach ; Electrophysiology ; Diet therapy ; Human ; Female ; Digestive system ; Feeding ; Digestive diseases ; Gastric disease ;

Mots-clés français / French Keywords

Premier trimestre ; Gestation ; Teneur protéine ; Repas ; Régime alimentaire enrichi ; Motilité ; Evacuation gastrique ; Vomissement ; Nausée ; Trouble fonctionnel ; Rythme ; Estomac ; Electrophysiologie ; Traitement diététique ; Homme ; Femelle ; Appareil digestif ; Alimentation ; Appareil digestif pathologie ; Estomac pathologie ;

Mots-clés espagnols / Spanish Keywords

Primer trimestre ; Gestación ; Contenido proteína ; Comida ; Régimen alimenticio enriquecido ; Motilidad ; Vaciamiento gástrico ; Vómito ; Nausea ; Trastorno funcional ; Ritmo ; Estómago ; Electrofisiología ; Tratamiento dietético ; Hombre ; Hembra ; Aparato digestivo ; Alimentación ; Aparato digestivo patología ; Estómago patología ;

Localisation / Location

INIST-CNRS, Cote INIST : 670 C2, 35400008804123.0140