Titre du document / Document title

High protein vs high carbohydrate hypoenergetic diet for the treatment of obese hyperinsulinemic subjects

Auteur(s) / Author(s)

HWALLA BABA N. ⁽¹⁾ ; SAWAYA S. ⁽¹⁾ ; TORBAY N. ⁽²⁾ ; HABBAL Z. ⁽¹⁾ ; AZAR S. ⁽¹⁾ ; HASHIM S. A. ⁽³⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Food Technology and Nutrition and the Division of Endocrinology, American University of Beirut, Beirut, LIBAN
⁽²⁾ Department of Functional Sciences. Universidad Centro-Occidental Lisandro Alvarado, VENEZUELA
⁽³⁾ Division of Metabolism, Department of Medicine, St Luke's Roosevelt Hospital and Columbia University, New York, ETATS-UNIS

Résumé / Abstract

OBJECTIVE: To test the hypothesis that hyperinsulinemic obese subjects would respond differently to changes in the composition of hypoenergetic diets. DESIGN: A 4-week randomized dietary intervention trial. SUBJECTS: Thirteen male obese hyperinsulinemic normoglycemic subjects were divided into two groups and fed hypoenergetic diets providing 80% of their resting energy expenditure (REE). One group received a high-protein diet (HP; 45% protein, 25% carbohydrates, and 30% fat as percent of dietary energy) and the other a high-carbohydrate diet (HC; 12% protein, 58 carbohydrates and 30% fat). MEASUREMENTS: Anthropometry, body composition, fasting serum insulin and lipids, and REE were performed before and after the feeding period. RESULTS: Weight loss was higher in the HP than HC group (8.3± 0.7 vs 6.0± 0.6 kg, P < 0.05). There was a decrease in body fat in both groups, whereas body water decreased significantly more in the HP group. REE decreased more in the HC than the HP group (- 384.3 ± 84.6 vs - 132.3 ± 51.0 kcal, P <0.05). Serum total cholesterol, triglycerides and LDL cholesterol decreased significantly to a similar extent in both diet groups, while HDL cholesterol was decreased significantly only in the HP group. Mean fasting insulin decreased significantly in both diet groups and reached the normal range only in the HP group. CONCLUSION: A low-carbohydrate (LC), HP hypoenergetic diet could be the diet composition of choice for a weight-reducing regimen in obese hyperinsulinemic subjects.

Revue / Journal Title

International journal of obesity   ISSN 0307-0565   CODEN IJOBDP 

Source / Source

1999, vol. 23, n^o11, pp. 1202-1206 (24 ref.)

Langue / Language

Anglais

Editeur / Publisher

Nature Publishing, Basingstoke, ROYAUME-UNI  (1977) (Revue)

Mots-clés anglais / English Keywords

Supplemented diet ; Low calorie diet ; Protein ; Carbohydrate ; Weight loss ; Obesity ; Hyperinsulinemia ; Comparative study ; Human ; Nutritional status ; Nutrition disorder ;

Mots-clés français / French Keywords

Régime alimentaire enrichi ; Régime alimentaire hypocalorique ; Protéine ; Glucide ; Perte poids ; Obésité ; Hyperinsulinémie ; Etude comparative ; Homme ; Etat nutritionnel ; Trouble nutrition ;

Mots-clés espagnols / Spanish Keywords

Régimen alimenticio enriquecido ; Régimen alimenticio hipocalórico ; Proteína ; Glúcido ; Adelgazamiento ; Obesidad ; Hiperinsulinemia ; Estudio comparativo ; Hombre ; Estado nutricional ; Trastorno nutricíon ;

Localisation / Location

INIST-CNRS, Cote INIST : 18243, 35400008075542.0130