Titre du document / Document title

Nasal strips do not affect pulmonary gas exchange, anaerobic metabolism, or EIPH in exercising thoroughbreds

Auteur(s) / Author(s)

GOETZ Thomas E. ; MANOHAR Murli ; HASSAN Aslam S. ; BAKER Gordon J. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

Departments of Veterinary Clinical Medicine and Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, ETATS-UNIS

Résumé / Abstract

The present study was carried out to examine whether nasal strip application would improve the exercise-induced arterial hypoxemia and hypercapnia, diminish anaerobic metabolism, and modify the incidence of exercise-induced pulmonary hemorrhage (EIPH) in horses. Two sets of experiments, control and nasal strip experiments, were carried out on seven healthy, sound, exercise-trained Thoroughbred horses in random order, 7 days apart. Simultaneous measurements of core temperature, arterial and mixed venous blood gases/pH, and blood lactate and ammonia concentrations were made at rest, during submaximal and near-maximal exercise, and during recovery. In both treatments, whereas submaximal exercise caused hyperventilation, near-maximal exercise induced significant arterial hypoxemia, desaturation of Hb, hypercapnia, and acidosis. However, O₂ content increased significantly with exercise in both treatments, while the mixed venous blood O₂ content decreased as O₂ extraction increased. In both treatments, plasma ammonia and blood lactate concentrations increased significantly with exercise. Statistically significant differences between the control and the nasal strip experiments could not be discerned, however. Also, all horses experienced EIPH in both treatments. Thus our data indicated that application of an external nasal dilator strip neither improved the exercise-induced arterial hypoxemia and hypercapnia nor diminished anaerobic metabolism or the incidence of EIPH in Thoroughbred horses performing strenuous exercise.

Revue / Journal Title

Journal of applied physiology   ISSN 8750-7587   CODEN JAPHEV 

Source / Source

2001, vol. 90, n^o6, pp. 2378-2385 (35 ref.)

Langue / Language

Anglais

Editeur / Publisher

American Physiological Society, Bethesda, MD, ETATS-UNIS  (1985) (Revue)

Mots-clés anglais / English Keywords

Gas exchange ; Lung ; Energy metabolism ; Anaerobe ; Physical exercise ; Hemorrhage ; Dilatator ; External ; Nostril ; Hypoxemia ; Hypercapnia ; Horse ; Animal ; Respiratory disease ; Lung disease ; Perissodactyla ; Ungulata ; Mammalia ; Vertebrata ;

Mots-clés français / French Keywords

Echange gazeux ; Poumon ; Métabolisme énergétique ; Anaérobie ; Exercice physique ; Hémorragie ; Dilatateur ; Externe ; Narine ; Hypoxémie ; Hypercapnie ; Cheval ; Animal ; Appareil respiratoire pathologie ; Poumon pathologie ; Perissodactyla ; Ungulata ; Mammalia ; Vertebrata ;

Mots-clés espagnols / Spanish Keywords

Intercambio gaseoso ; Pulmón ; Metabolismo energético ; Anaerobio ; Ejercicio físico ; Hemorragia ; Dilatador ; Externo ; Narina ; Hipoxemia ; Hipercapnia ; Caballo ; Animal ; Aparato respiratorio patología ; Pulmón patología ; Perissodactyla ; Ungulata ; Mammalia ; Vertebrata ;

Localisation / Location

INIST-CNRS, Cote INIST : 5400, 35400009899510.0460