Titre du document / Document title

Coagulation studies in preoperative neurosurgical patients

Auteur(s) / Author(s)

SCHRAMM B. ⁽¹⁾ ; LESLIE K. ⁽¹⁾ ; MYLES P. S. ^{(2 3)} ; HOGAN C. J. ⁽⁴⁾ ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

⁽¹⁾ Department of Anaesthesia and Pain Management, Royal Melbourne Hospital, Melbourne, AUSTRALIE
⁽²⁾ Department of Anaesthesia and Pain Management, Alfred Hospital, Melbourne, AUSTRALIE
⁽³⁾ Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, AUSTRALIE
⁽⁴⁾ Department of Haematology, Royal Melbourne Hospital, Melbourne, AUSTRALIE

Résumé / Abstract

Unselected preoperative coagulation testing is known to have low positive yield. However, no study has specifically evaluated neurosurgical patients. A retrospective study of 1211 patients having neurosurgery over a one-year period was therefore conducted. Preoperative test results (activated partial thromboplastin time [aPTT], prothrombin time [PT] and platelet count) and historical factors indicating a potential bleeding tendency were recorded. Abnormality was defined as a test result outside the normal range for our laboratory. Seventeen per cent of all test results were abnormal. However, if abnormality was redefined as a test result indicating potential bleeding tendency (low platelet count, prolonged aPTT and/or PT), only 7.2% of results were abnormal. Many patients had factors on history indicating a potential bleeding tendency, but only a prolonged aPTT, cranial surgery and the use of anti-hypertensive and anaesthetic drugs preoperatively predicted postoperative bleeding. Prolonged aPTT was predictable on history in most patients. We conclude that routine screening of all preoperative neurosurgical patients in our hospital is unnecessary.

Revue / Journal Title

Anaesthesia and intensive care   ISSN 0310-057X   CODEN AINCBS 

Source / Source

2001, vol. 29, n^o4, pp. 388-392 (10 ref.)

Langue / Language

Anglais

Editeur / Publisher

Anaesthesia and Intensive Care, Edgecliff, AUSTRALIE  (1972) (Revue)

Mots-clés anglais / English Keywords

Surgery ; Nervous system diseases ; Human ; Hemorrhage ; Complication ; Evaluation ; Preoperative ; Blood coagulation ; Coagulation test ; Partial thromboplastin time ; Prothrombin time ; Platelet ; Medical screening ; Coagulopathy ; Postoperative ; Prediction ;

Mots-clés français / French Keywords

Chirurgie ; Système nerveux pathologie ; Homme ; Hémorragie ; Complication ; Evaluation ; Préopératoire ; Coagulation sanguine ; Test coagulation ; Temps thromboplastine partielle ; Temps prothrombine ; Thrombocyte ; Dépistage ; Coagulopathie ; Postopératoire ; Prédiction ;

Mots-clés espagnols / Spanish Keywords

Cirugía ; Sistema nervioso patología ; Hombre ; Hemorragia ; Complicación ; Evaluación ; Preoperatorio ; Coagulación sanguínea ; Prueba coagulación ; Tiempo tromboplastina parcial ; Tiempo protrombina ; Trombocito ; Descubrimiento ; Coagulopatía ; Postoperatorio ; Predicción ;

Localisation / Location

INIST-CNRS, Cote INIST : 17481, 35400009716771.0090