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Titre du document / Document title

Incidence of Candida in psoriasis: a study on the fungal flora of psoriatic patients

Auteur(s) / Author(s)

WALDMAN A. (1 2) ; GILHAR A. (2) ; DUEK L. (1) ; BERDICEVSKY I. (1) ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

(1) The Department of Microbiology, Rappaport Institute, Faculty of Medicine, Technion, Institute of Technology, Haifa, ISRAEL
(2) Laboratory of Dermatological Research, Rappaport Institute, Faculty of Medicine, Technion, Institute of Technology, Haifa, ISRAEL

Résumé / Abstract

The presence of Candida albicans and other Candida species in saliva and faeces of 50 psoriatic patients compared with a control group of 50 healthy donors was examined quantitatively. The quantity of Candida in saliva and faeces of the psoriatics proved to be significantly higher than in the controls. Candida was detected in 78% of the saliva samples of the psoriatics but in only 50% of the controls, and in the faeces samples in 72% of the psoriatics, but in only 46% of the controls. Qualitative analysis revealed a predominance of Candida albicans (saliva, 77%; faeces, 64%) and Candida rugosa (saliva, 28%; faeces, 28%). We did not find a correlation between the severity of the psoriasis according to the Psoriasis Area and Severity Index and the amount of Candida in the saliva or in the faeces. Our results reinforce the hypothesis that C. albicans is one of the triggers to both exacerbation and persistence of psoriasis. We propose that in psoriatics with a significant quantity of Candida in faeces, an antifungal treatment should be considered as an adjuvant treatment of psoriasis.

Revue / Journal Title

Mycoses    ISSN  0933-7407 

Source / Source

2001, vol. 44, no3-4, pp. 77-81 (25 ref.)

Langue / Language

Anglais

Editeur / Publisher

Blackwell, Berlin, ALLEMAGNE  (1988) (Revue)

Mots-clés anglais / English Keywords

Psoriasis

;

Incidence

;

Candida

;

Candidiasis

;

Human

;

Fungi Imperfecti

;

Fungi

;

Thallophyta

;

Mycosis

;

Infection

;

Epidemiology

;

Skin disease

;

Mots-clés français / French Keywords

Psoriasis

;

Incidence

;

Candida

;

Candidose

;

Homme

;

Fungi Imperfecti

;

Fungi

;

Thallophyta

;

Mycose

;

Infection

;

Epidémiologie

;

Peau pathologie

;

Mots-clés espagnols / Spanish Keywords

Psoriasis

;

Incidencia

;

Candida

;

Candidiasis

;

Hombre

;

Fungi Imperfecti

;

Fungi

;

Thallophyta

;

Micosis

;

Infección

;

Epidemiología

;

Piel patología

;

Localisation / Location

INIST-CNRS, Cote INIST : 4156 B, 35400009766941.0030

Nº notice refdoc (ud4) : 1021742



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